Role of novelty seeking personality traits as mediator of the association between COMT and onset age of drug use in Chinese heroin dependent patients.
Personality traits such as novelty seeking (NS) are associated with substance dependence but the mechanism underlying this association remains uncertain.Previous studies have focused on the role of the dopamine pathway.Examine the relationships between allelic variants Beauty of the catechol-O-methyltransferase (COMT) gene, NS personality traits, a